ABSTRACT
I. Introduction .................................................................................................. 291 II. Low Folate Status and Risk of Cardiovascular Disease ............................... 293 III. Metabolic Consequences of Low Folate Status
in Cardiovascular Disease ............................................................................294 A. Hyperhomocysteinemia ...........................................................................294 B. Hypomethylation ...................................................................................... 295 C. DNA Synthesis and Repair ......................................................................296
IV. The Vascular Endothelium and Cardiovascular Health ...............................296 A. Endothelial Cell Dysfunction and Risk of Cardiovascular Disease ........296 B. Measurement of Endothelial Function .....................................................297 C. Clinical Studies Using Flow-Mediated Dilatation ...................................297
