ABSTRACT

Numerous studies have demonstrated that leukotriene receptor antagonism and synthesis inhibition can blunt the bronchospastic response to allergen, exercise, and aspirin; all are forms of induced asthma rather than spontaneous asthma. Currently only six studies published in the archival literature describe the effects of these agents in chronic stable asthma. We will describe these studies and then comment on the implications of these studies vis-a`-vis the role of these agents in the treatment of asthma.