ABSTRACT
Sensitive skin is a clinical syndrome, first described in the 1960s by Thiers (1). In the 1970s, Frosch and Kligman (2) described the initial protocol of the lactic acid stinging test. Then, a lot of interest to the field sensitive skin was increasing on this “subjective discomfort, namely, delayed stinging or smarting from topical agents applied to the skin” (2). Since the skeptical opinion expressed by Maibach (3) at the end of the 1980s stated that “the plausibility of the concept of the sensitive skin evokes discussion and often amusement because of the variance of the number of opinions compared with the amount of data, at least until recently,” significant progress has been made. Now, all the authors agree now that sensitive skin is a reality.
