ABSTRACT
INTRODUCTION As the outermost layer of the skin, the stratum corneum (SC) participates in the functional properties of the skin (1). It protects our body from harsh environmental factors and mechanical insults. In the meantime, its ability to distort and its softness are responsible for the comfort of the skin. Many cosmetic treatments rely on the application and transfer of materials onto the skin surface to restore or improve its properties. Knowledge of the subtle changes occurring in the stratum corneum is essential to develop targeted ingredients and most appropriate skin care products.
