ABSTRACT

An increasing interest has been noted recently on various modifi cations to classical freeze-drying (F-D) such as sublimation under atmospheric pressure (see Chapter 21) and sublimation into a fl uid bed of solid adsorbents (Boeh-Ocansey, 1988; Lombrana and Villaran, 1996; Lombrana, 1997). A step forward in producing materials of unique properties is sprayfreeze-drying (SF-D), which offers free-fl owing, ultrafi ne, and uniform particles with high surface area, porosity, and enhanced solubility. Thus, SF-D has a great potential for producing drugs, nutraceuticals, functional foods, advanced materials, and other high-value products.