ABSTRACT
Simulation plays an important role in the development of positron emission tomography (PET). It is used extensively in the design of tomographs, in the investigation of physical effects that cannot be quanti‰ed using experiments, in the development of data correction and image reconstruction algorithms, and in the development of imaging protocols. Simulation studies have led to understanding the effect of scatter on PET images, the optimal design of septa, the effects of noise on PET images, and the sensitivity and resolution limits of PET. Simulation continues to be used in these areas for PET and other image modalities [1-3].
