ABSTRACT
This chapter describes an electrochemical biosensor system, the eSystem, for measurement of cancer gene expression and explains its potential use in research on cancer drugs, in the diagnosis and treatment of cancer, how the biosensors are created, how they function, and how they can be applied in point-of-care settings. The aim is to describe research and development of the eSystem by Alderon Biosciences (Beaufort, NC) and potential use of its disposable biosensors for the measurement of cancer gene expression. Because the eSystem is small, portable, and robust, it can be used in point-of-care settings and play a key role in the further development and application of truly personalized medicine. The eSystem characteristics, further described in this chapter, thus show that this state-of-the-art electrochemical technology is poised for use in cancer research and could play a signicant role in cancer drug development and in the improved early detection and treatment of cancers.
