ABSTRACT
The diagnosis of palmar and/or plantar psoriasis is usually uncomplicated, especially when typical anatomic sites are involved. However, in cases with only palmar and/or plantar involvement, it may be troublesome, often requiring skin biopsy with histopathological evaluation. Differential diagnosis includes eczematous dermatitis (allergic, irritative), tinea manuum/ pedis, lichen planus, porokeratosis, pityriasis rubra pilaris, keratodermas, mycosis fungoides, epidermolysis bullosa, syphilis, scabies, and drug reactions.
