ABSTRACT
Information gathered from the direct measurement of the cortex and subcortical structures has been central to the current understanding of epilepsy and its treatment. As measurement of the brain improves with the advent of new sensor modalities and technologies, so does our understanding of epilepsy and options for its control. Direct measurement of the brain in epilepsy and the possibility of intervention to control the expression of this disorder has been a long-lasting interdisciplinary effort involving engineers, physicists, mathematicians, epileptologists, neuroscientists, and neurosurgeons. However, transitioning new and emerging technologies fostered in academic, research, medical, and industrial environments into a successful product presents unique challenges. This chapter reviews some of the emerging technologies for brain-implantable devices for epilepsy and the challenges for their manufacture and commercialization.
