ABSTRACT

The P subunit of MMOH shares structural similarities with the N-terminal a-helical bundle domain of the a subunit, although no sequence homology exists between them. The y domain is formed by eight short a helices that interface with both the a and the P subunits. The structure of the regulatory protein B has been recently solved and reveals a one domain a-P protein. No structure has been determined for MMOH complexed with protein B or the reductase [192,193].