ABSTRACT

Exposure to high levels of dust is required to diagnose ODTS but not HSP. ODTS also is clearly distinct from reactive airways dysfunction syndrome (RADS), since the latter requires inhalation of high levels of irritants and leads to persistent bronchial hyperreactiv­ ity, whereas ODTS resolves without adverse sequelae. This also distinguishes ODTS from chronic bronchitis or byssinosis, which may lead to persistent changes in airway structure and function.