ABSTRACT

Tobacco use is the leading underlying cause of death in the United States (1) and likewise is an important public health problem in Nebraska. During 2010, prevalence of adult smoking in Nebraska was 18.4%, similar to the national average of 19.0% (2,3). Preventing or delaying the onset of tobacco use is a key component in decreasing the occurrence of premature deaths. Understanding the genetic and environmental factors that predispose people to tobacco use is important. One area of study that has received substantial interest involves childhood adverse events. Experiencing childhood sexual and physical abuse and witnessing violence in the home or community substantially increase the risk of tobacco initiation and dependence (4-6).