ABSTRACT

Cancer is prevalent worldwide and impacts not only millions of people but also their families, carers, and even employers. Cancer impacts people’s physical, cognitive, and functional ability as well as their health-related quality of life and economic well-being. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Lung cancer is one of the leading causes of cancer-related deaths in the world and accounts for nearly 1.4 million deaths per year worldwide, with a yearly incidence of over 41,000 in the UK alone. The economic burden of treating cancer is high worldwide. Cancer has the most devastating economic impact in the world compared to other diseases. Common approaches for treating cancer include surgery, followed by chemotherapy, and radiotherapy. In 2014, the cost of every new cancer drug approved in the US exceeded $120,000 per year of treatment. For most drugs, sales are usually somewhat flat during the period between market authorization and reimbursement.