ABSTRACT

Decrease in effectiveness of therapy by the antibiotics, being observed recently, is caused, generally distribution of strains of bacteria steady against them. Polymeric derivatives of antibiotics can help with the solution of this task.1 Advantages of use of polymeric derivative antibiotics are obvious in that case when polymer carrier of medicinal substance is in a soluble form. However, it is not less important to consider the case when polymer carries out a matrix role-the carrier of medicinal substance. In this work, some approaches to creation of sheet having antibacterial coverings on the basis of chitosan (ChT) of the prolonged action suitable for treatment of surgical, burn, and slow wounds of a various etiology are considered. The choice as the ChT carrier is not casual as this polymer possesses the whole range of the unique properties doing it by irreplaceable polymer2 for medicine.