ABSTRACT
Abstract ................................................................................................... 14 2.1 Introduction .................................................................................... 14 2.2 Experimental Part ........................................................................... 15 2.3 Results and Discussion .................................................................. 19 2.4 Conclusion ..................................................................................... 28 Keywords ................................................................................................ 28 References ............................................................................................... 29
ABSTRACT
Hydrogels on the base of dialdehyde of hyaluronic acid (DHA) and chitosan, modified by succinic anhydride (MCTS), with entrapped mitomycin C (MMC) are obtained for antiglaucoma filtering surgery in ophthalmology. Such hydrogels contain no toxic cross-links and cross-linkers due its formation is related to cross-links –C=N-(between aminogroups of MCTS and aldehyde groups of DHA) called as Schiff base. The effect of way formation of solutions on retention of mitomycin C from hydrogels is studied.
