ABSTRACT
Dental restorative materials such as composites, glass ionomer cements, and adhesive systems are being widely used; however, they still have several drawbacks. Tooth restorations often fail and the replacement of failed restorations accounts for 50%–70% of all tooth cavity restorations performed. Nanotechnology has been applied to develop the next generation of dental restorative materials with desirable bioactive proprieties, to not only replace the missing tooth volume but also exert therapeutic effects to combat caries. Recurrent caries lesions around restorations have been the main reason for operative treatment failures. These lesions are related to oral biolm accumulation and acid production. Nanomaterials with large surface-to-volume ratios and unique physical, chemical, and biological properties have demonstrated great potential to inhibit the formation of biolms with improved caries inhibition efcacy. This chapter summarizes the ongoing advancement in studies
6.1 Introduction .................................................................................................. 152 6.2 Antibacterial Composites and Bonding Agents with Silver Nanoparticles ... 153 6.3 Remineralizing Composites and Bonding Agents with Calcium
Phosphate Nanoparticles ............................................................................... 158 6.4 Combining NAg with Quaternary Ammonium and NACP in Restorations ... 162 6.5 Other Nanostructured Antibacterial and Remineralizing Restoratives ....... 164 6.6 Conclusion .................................................................................................... 165 Acknowledgments .................................................................................................. 165 References .............................................................................................................. 165
of emerging functionalized nanoparticles as strategies for addressing dental restorative challenges. This includes new nanomaterials with potent antibacterial activity as well as remineralization capability, the combination of several bioactive agents together in resin for effective caries inhibition, and their promising in vitro properties and in vivo performance. Furthermore, research trends and future prospects in the area of resin-based dental materials with a wide range of applications in dental caries management are discussed. In addition, this chapter attempts to provide a glance into the potential future of these new nanomaterials to researchers in dental materials science, dental practitioners, and investigators in other related elds.
