A Review of the Pivotal Studies Supporting the Use of Periconceptional Multivitamins in the Prevention of Congenital Abnormalities

As the beginning of life is conception, followed by the very sensitive period of fetal development, dietary deciencies associated with risk of fertility, pregnancy complications, birth defects, preterm

5.1 Introduction ............................................................................................................................ 89 5.2 Previous Intervention Trials ...................................................................................................90 5.3 The Hungarian Periconception Service ..................................................................................90 5.4 Preparation of the HRCT ........................................................................................................ 91 5.5 Primary Results of the HRCT ................................................................................................92 5.6 Secondary Results of the HRCT .............................................................................................93