ABSTRACT

One of the most important biological properties of dimethyl sulfoxide (DMSO) is its ability to protect cells from radiation damage.1 DMSO has been used in a number of studies to repair radiation damage induced in a variety of mammalian models and in vitro preparations.2 Such radiation damage to mammalian cells generally involves injury to deoxyribonucleic acid (DNA). DNA molecules are double-stranded helices running in opposite directions to each other. In mammals, most of the DNA is stored inside the cell nucleus in a dense string-like ber called chromatin.