ABSTRACT

Living donor lobar lung transplantation (LDLLT) was introduced by Starnes and colleagues as an alternative form of treatment for patients who experience a decline in physical condition and have limited life expectancy. In the beginning a single donor was used, and successful living donor single-lobe transplantation was reported. 1 However, subsequent experience with single-lobe transplantation was not satisfactory. It is for this reason that Starnes’ group developed bilateral LDLLT, in which two healthy donors donate their right or left lower lobes (Figure 18.1). 2 , 3 Because only two lobes are transplanted, LDLLT seems to be best suited for children and small adults, and in the group’s experience it has been applied almost exclusively in patients with cystic fibrosis. 3 However, LDLLT is now well known to be applicable in cases of restrictive, obstructive, infectious, and hypertensive lung disease in both pediatric and adult patients when the size matching is acceptable. 4–6 Bilateral living donor lobar lung transplantation. The right and left lower lobes from two healthy donors are implanted in a recipient in place of whole right and left lungs, respectively. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9780429157523/9cb45195-0799-420e-9622-a2fda40bb839/content/fig18_1.jpg"/>