ABSTRACT
DEFINITION Raynaud’s’ phenomenon (RP) is an exaggerated response to cold temperature or emotional stress that results in transient digital ischemia. RP is considered primary if these symptoms occur alone without evidence of any associated rheumatic disorders. RP is considered secondary when it occurs as a manifestation of another health condition or exposure. Rheumatic conditions associated with secondary RP include scleroderma (SSc) (where RP is nearly universal), lupus, Sjögren’s syndrome, dermatomyositis, mixed connective tissue disease (MCTD), and rheumatoid arthritis (RA).
