ABSTRACT

Clinical features The clinical presentation, as depicted by the two reported cases, is varied. The first case was a generalized skin eruption with large bullae that became hemorrhagic [2]. The lesions first appeared in the oral cavity but rapidly spread to all skin areas within 2 days. The blisters, ranging from a few millimeters to a few centimeters in diameter, affected the torso, buttocks, arms, legs, hands, and feet, and covered approximately 60% of the total skin surface (192, 193). When the bullae broke, they left large painful and denuded areas, resembling a generalized desquamation like that of toxic epidermal necrosis or SSSS. The lesions subsequently healed without obvious scarring.