ABSTRACT

AIIRB angiotensin II receptor blocker

AAFB acid-alcohol fast bacilli ACE angiotensin-converting

enzyme ACTH adrenocorticotrophic

hormone ADH antidiuretic hormone AF atrial fibrillation AIDS acquired immune-

deficiency syndrome AIN acute interstitial nephritis AIP acute intermittent

porphyria ALA aminolaevulinic acid ALT alanine transaminase

(SGPT) AML acute myeloid leukaemia AMP adenosine 5'-

monophosphate ANA antinuclear antibody ANCA antineutrophil cytoplasmic

antibodies ANF antinuclear factor APCKD adult polycystic kidney

disease APTT activated partial

thromboplastin time AR aortic regurgitation ARDS adult respiratory distress

syndrome ARVC arrhythmogenic right

ventricular cardiomyopathy AS aortic stenosis ASD atrial septal defect ASO antistreptolysin AST aspartate transaminase

(SGOT) ATN acute tubular necrosis AZT zidovudine BCG bacille Calmette-Guérin BIH benign intracranial

hypertension BP blood pressure BT bleeding time BTS British Thoracic Society CAH chronic active hepatitis CAP community acquired

pneumonia CCF congestive cardiac failure CFTR cystic fibrosis

transmembrane regulator (protein)

CML chronic myeloid leukaemia CMV cytomegalovirus COPD chronic obstructive

pulmonary disease CPAP continuous positive airway

pressure CREST calcinosis, Raynaud’s

syndrome, oesophageal problems, scleroderma, telangiectasia

CRF chronic renal failure CRP C-reactive protein CSF cerebrospinal fluid CSS Churg-Strauss syndrome CT computed tomography CVA cerebrovascular accident CVP central venous pressure CXR chest X-ray DBP diastolic blood pressure DC direct current DHCC dihydroxy-cholecalciferol DIC disseminated intravascular

coagulation DIDMOAD diabetes insipidus,

diabetes mellitus, optic atrophy and deafness

DM diabetes mellitus DT delerium tremens DVT deep-vein thrombosis EAA extrinsic allergic alveolitis EBV Epstein-Barr virus ECG electrocardiogram EEG electroencephalogram ELISA enzyme-linked

immunosorbent assay EMF endomyocardial fibrosis EMG electromyogram ENT ear, nose and throat EPO erythropoietin ERCP endoscopic retrograde

cholangiopancreatogram ESR erythrocyte sedimentation

rate FBC full blood count FDP fibrinogen degradation

product FES fat embolism syndrome FEV1 fixed expiration volume in

1 second FFP fresh-frozen plasma FNA fine-needle aspiration FSH follicle stimulating

hormone FTA fluorescent treponemal

antibody

FVC forced vital capacity GBM glomerular basement

membrane GCT giant cell tumour GFR glomerular filtration rate GH growth hormone GHRH growth hormone releasing

hormone GI gastrointestinal GP general practitioner GPI glucophosphatidylinositol GT glutamyltransferase GTN glyceryl trinitrate Hb haemoglobin HbSS sickle cell anaemia HC Hereditary Copro

porphyria HCC hydroxy-cholecalciferol HCM hypertrophic

cardiomyopathy HCV hepatitis C virus HCG human chorionic

gonadotrophin HELLP haemolysis, elevated liver

enzymes and low platelets HHT hereditary haemorrhagic

telangiectasia HIT heparin-induced

thrombocytopenia HIV human immunodeficiency

virus HONK hypersimilar non-ketotic

diabetic coma HR heart rate HRT hormone replacement

therapy HS hereditary spherocytosis HSMN hereditary sensorimotor

neuropathy HUS haemolytic uraemic

syndrome ICD implantable cardioverter

defibrillator ICP intracranial pressure INR International Normalized

Ratio IPF idiopathic pulmonary

fibrosis IVP intravenous pyelogram IVU intravenous urogram JVP jugular venous pressure KCO corrected carbon monoxide

transfer factor LBBB left bundle branch block LDH lactate dehydrogenase

LFT liver function tests LH luteinizing hormone LHON Leber’s hereditary optic

neuropathy LHRH luteinizing hormone

releasing hormone LMWH low-molecular weight

heparin LQTS long QT-syndrome LVEDP left ventricular end-diastolic

pressure LVH left ventricular hypertrophy MAHA microangiopathic

haemolytic anaemia MAOI monoamine oxidase

inhibitor MCH mean cell haemoglobin MCHC mean cell haemoglobin

content MCV mean cell volume MELAS mitochondrial

encephalopathy, lactic acidosis, stroke-like syndrome

MEN multiple endocrine neoplasia

MERRF myoclonic epilepsy and red ragged fibres

MGUS monoclonal gammopathy of undetermined significance

MPO myeloperoxidase MR mitral regurgitation MRA magnetic resonance

angiography MRCP magnetic resonance

cholangiopancreatogram MRI magnetic resonance

imaging MRSA methicillin resistant

Staphylococcus aureus MRV magnetic resonance

venography MSH melanocyte stimulating

hormone NADPH nicotinamide adenine

dinucleotide phosphate (reduced)

NAPQI N-acetyl-pbenzoquinoneimine

NARP neuropathy, ataxia, retinitis pigmentosa

NASH non-alcoholic steatohepatitis

NIPPV non-invasive positive pressure ventilation

NSAID non-steroidal antiinflammatory drug

NSTEMI non-ST elevation myocardial infarction

NYHA New York Heart Association

OSA obstructive sleep apnoea PAN polyarteritis nodosa PAS periodic acid-Schiff PBC primary biliary cirrhosis PBG porphobilinogen PCOS polycystic ovary syndrome PCR polymerase chain reaction PCT porphyria cutanea tarda PCV packed cell volume PCWP pulmonary capillary wedge

pressure PE pulmonary embolism PEFR peak expiratory flow rate PFO patent foramen ovale PKD polycystic kidney disease PMLE progressive multifocal

leucoencephalopathy PMR polymyalgia rheumatica PNH paroxysmal nocturnal

haemoglobinuria PRL prolactin PRV polycythaemia rubra vera PSC primary sclerosing

cholangitis PT prothrombin time PTH parathormone or

parathyroid hormone PVE prosthetic valve

endocarditis RA rheumatoid arthritis RBBB right bundle branch block REM rapid eye movement RMAT rapid macroagglutination

test RTA renal tubular acidosis RV residual volume SADS sudden adult death

syndrome SAM systolic anterior motion of

the mitral valve SAP serum amyloid protein SIADH syndrome of inappropriate

antidiuretic hormone SLE systemic lupus

erythematosus SMA smooth muscle antibody SPECT single photon emission

computed tomography SROS Steele-Richardson-

Olszewski syndrome STEMI ST elevation myocardial

infarction SVT supraventricular tachycardia TB tuberculosis

TCAD tricyclic antidepressant overdose

TIA transient ischaemic attack TIBC total iron-binding capacity TIPSS transjugular intrahepatic

portosystemic shunt TLC total lung capacity TLCO total lung carbon

monoxide transfer factor TOE transoesophageal

echocardiography TPA tissue plasminogen

activator TPHA treponema pallidum

haemagglutination test TRH thyrotrophin releasing

hormone TSAT transferrin saturation TSH thyroid stimulating

hormone TT thrombin time TTP thrombotic

thrombocytopenic purpura U&E urea and electrolytes URTI upper respiratory tract

infection US ultrasound UTI urinary tract infection VDRL Venereal Diseases Research

Laboratory test VF ventricular fibrillation VIP vasointestinal polypeptide VMA vanilyl mandelic acid VP variegate porphyria VR ventricular rate VSD ventricular septal defect VT ventricular tachycardia WCC white cell count WPW Wolff-Parkinson-White

(syndrome)

A 49-year-old male presented to the Accident and Emergency Department with a one-hour history of severe central chest pain. He smoked 30 cigarettes per day. Physical examination was normal. The 12-lead ECG revealed ST segment elevation in leads V1-V4. There were no contraindications to thrombolysis.