ABSTRACT
Migraine is a recurring, debilitating primary headache condition affecting approximately 17% of women and 6% of men annually in the United States (Diamond et al. 2007), though the recent Global Burden of Disease study recorded slightly higher worldwide rates at 18.8% in women and 10.7% in men (Vos et al. 2012). There are two major subtypes; migraine with and without aura. Migraine without aura is classified in individuals who have had at least five headache attacks lasting 4-72 h, with pain characteristics that fulfill two or more of the following: moderate to severe intensity; unilateral location; pulsating quality; or aggravation upon routine physical activity or avoidance thereof, and is accompanied by nausea, vomiting, photophobia or phonophobia (Headache Classification Committee of the IHS 2013). Migraine with aura occurs when an individual experiences reversible sensory disturbances (most frequently in the form of visual aura) with headache, which may or may not meet the criteria of migraine without aura.
