ABSTRACT
Endometrial cancer usually arises in post-menopausal women. Endometrial cancer is the most common cancer in women in the UK. The incidence of endometrial cancer is four-fold higher in developed countries and is significantly higher in Wales compared to the other constituent countries of the UK. A epidemiological study has indicated that the malignancy most strongly associated with obesity is endometrial cancer. The highest risk of hormone replacement therapy is for atypical endometrial hyperplasia, but there is also an effect on advanced cancer and mortality. The International Federation of Gynecology and Obstetrics Committee on Gynaecologic Oncology recommend that endometrial cancer is surgically staged. Endometrial cancer usually presents with vaginal bleeding in post-menopausal women. Transvaginal ultrasound scanning is an accurate method of excluding endometrial cancer. Women can be assessed quickly and triaged for endometrial biopsy on the basis of their scan findings.
