ABSTRACT

Quantum dots (QDs) are widely studied as luminescence probes in biological

and medical research in recent years. Compared with the conventional dyes

used as imaging probes, QDs have several advantages in optical and chemical

properties such as tunable emission from visible to infrared wavelengths by

changing their size and composition, broader excitation spectra due to high

absorption coefficients, high quantum yield of fluorescence, strong brightness,

photo stability, and high resistance to photobleaching. These unique properties

of QDs have attracted tremendous interest in exploiting them in a variety of

biological field [1-3]. However, the potential applications of quantum dots in

biology andmedicine were limited due to the toxic effects of semiconductor QDs,

which have received enormous attention over the past few years. In order to

reduce the cytotoxicity of QDs, two strategies were devised.