ABSTRACT
Pathogenesis Physiologic Considerations Although numerous diseases ranging from acute metritis to pleuropneumonia can predispose horses to the development of acute laminitis, the most common instigator of laminitis is acute abdominal disease.1 Acute laminitis is commonly associated with horses exhibiting signs consistent with endotoxemia owing to compromised bowel in diseases that require surgical intervention (e.g., intestinal strangulation obstruction) and horses with severe inflammatory bowel diseases (e.g., colitis, proximal enteritis).2
