ABSTRACT

Advances in the understanding of the molecular mechanisms implicated in prostate cancer progression have identified many potential therapeutic gene targets that are involved in apoptosis, growth factors, cell signaling, and the androgen receptor (AR). A critical factor responsible for the malignant progression of prostate cancer is the abnormal expression and function of specific proteins. From the transcription of messenger RNA (mRNA) to the translation of proteins and their function, several steps can be exploited as ‘‘drugable’’ targets.