ABSTRACT
To sustain life, all of our body organs and tissues must be soaked in tissue fluid, and our body should be covered with a barrier that prevents water loss. The raison d’etre of the skin on our body surface is to produce the stratum corneum (SC) barrier that protects our body from desiccation (1). Just imagine clinical situations in which the skin surface is extensively lacking, such as pemphigus vulgaris, epidermolysis bullosa, toxic epidermal necrolysis, or burn. They all present a serious problem for survival.
