ABSTRACT
In as early as 1910, Peptostreptococci had been isolated from cases of puerperal sepsis. The prerequisite for infection is a low oxidation-reduction potential, such as that provided by grossly traumatized or devitalized tissue. Not infrequently, a synergistic relationship exists with either Gardnerella vaginalis or the Bacteroidaceae. The G. vaginalis-Peptostreptococci coinfection occurs more frequently in obstetric patients, whereas the Bacteroides-Peptostreptococci are more common synergistic pathogens in gynecologic patients. Given the conditions permitting anaerobic growth, the initial infection is endometritis. The signs of infection include a foulsmelling lochia that is usually followed by pyrexia. If infection is the consequence of retained septic products of conception, the process spreads through the partially thrombosed sinuses at the placental site and gains access to the uterine and ovarian veins. The process may not progress beyond this point, with resolution of the infection occurring gradually over several weeks.
