ABSTRACT

Crohn’s disease (CD) is a chronic focal, transmural, and granulomatous inflammatory disorder that can affect any portion of the gastrointestinal tract. The condition was first described by Crohn, Ginzburg, and Oppenheimer in 1932 as an inflammatory condition limited to the terminal ileum (1). It was not until 1960 that it was recognized that the disease could affect the colon alone as an entity distinct from ulcerative colitis (UC) (2). This chapter reviews the etiology, clinical presentation, diagnosis, and medical and surgical management of CD of the colon.