ABSTRACT

The effects of hormones in acne are most notable in women. Androgens such as dihydrotestosterone (DHT) and testosterone, the adrenal precursor dehydroepiandrosterone sulfate (DHEAS), estrogen, and other hormones, including growth hormone or insulin-like growth factors (IGFs), may each be important. It is likely that the hormones affecting the sebaceous gland are both taken up from the serum in addition to being made locally within the gland.