ABSTRACT
I. INTRODUCTION sound knowledge of the underlying mathematical principles of membrane transport is essential if we are to expand our understanding of how membrane barriers fulfill their function and how we can alter their properties to our advantage. The subject of the mathematics of diffusion are enough to fill entire books (1), but in this chapter we have attempted to pick out those mathematical solutions and descriptions that are both commonly used and most appropriate in the field of percutaneous absorption. It is the purpose of this work to attempt to present these equations in a manner that will enable readers to apply them to real numbers generated in their laboratories.
