ABSTRACT
The study of experimental animal models of human ocular disease comprises an important area of research in ophthalmology and the visual sciences. As early as 1882, animal models were being developed for human diseases [1]. Although investigators have been attempting to develop animal models of human cancer over the past century, the availability of relevant animal models of human ocular melanoma is relatively recent. An animal model for the study of intraocular melanoma should ideally exhibit tumors that have similarities in their pathogenesis, morphology, and molecular biology to human uveal melanoma. In this review, we summarize what is currently known about animal models of human uveal melanoma [2].
