ABSTRACT
Retinoblastoma, first described by Pawius in 1657, virtually disappeared from the medical literature for 150 years [1]. Between 1767 and 1847, numerous cases were reported in Europe. In 1809, Wardrop published 35 cases of retinoblastoma treated successfully with enucleation, after which enucleations for retinoblastoma became widespread [2]. In the United States, the first case report appeared in 1818 in the register of The New York Hospital. The modern era of radiotherapy began with Reese and Martin at the Columbia Presbyterian Medical Center in New York in 1936 [1].
