ABSTRACT

Uveal melanoma is a rare disease but is the most common primary intraocular tumor and has a high potential for metastasis. The study of factors that determine the occurrence and distribution of this disease is critical in the understanding of its possible prevention. Previous knowledge of the epidemiology of uveal melanoma has been reviewed extensively [1-4], and we recommend these excellent readings. In the present chapter, we discuss the challenges associated with the epidemiologic study of uveal melanoma, review the current knowledge of its incidence and possible risk factors for diagnosis in light of new evidence, and outline future directions for epidemiologic research.