ABSTRACT

Deep brain stimulation (DBS) has been performed in the last decade for medi-

cally refractory Parkinson’s disease (PD) as an alternative to ablative stereotactic

neurosurgical procedures (1-7). DBS of the subthalamic nucleus (STN) and the

globus pallidus internas has essentially replaced pallidotomy and thalamotomy as

the procedure of choice for PD. In contrast to ablative stereotactic procedures,

DBS does not require destructive brain lesions and, therefore, lessens the risk

of permanent postoperative neurological deficits. Pathological studies have

demonstrated that DBS does not cause damage to the adjacent tissue, except

for mild gliosis around the implanted electrode track (8).