ABSTRACT

Narcolepsy is a disorder characterized by two major symptoms, namely, excessive daytime sleepiness (EDS) and cataplexy, with a great variability in its presentation. EDS is, in most cases, the first symptom to occur but narcolepsy may start with cataplexy in both adult and prepubertal narcoleptic patients (1). Symptoms may start abruptly with facility to pinpoint the onset of narcolepsy, but it may appear progressively, insidiously, with in some cases sudden worsening of severity. In larger surveys of narcoleptic patients, the mean age at onset was estimated to be in the early 20s. Indeed, Guilleminault et al. (2) studied 410 subjects where the mean age at onset of daytime hypersomnia was 23.7+ 12.9 years (median age, 20.9 years).