ABSTRACT

Coating with molecules or polymer around nanoparticles is important for their protection and functionalization. This chapter summarizes various coating procedures for different nanoparticles. Coating methods are selected based on their general utility to different nanoparticles and advantages in deriving various functional nanoparticles. Attempts have been made to focus on the coating methods that are most reliable with good reproducibility. Coating methods include silica coating, polyacrylate coating, lipophilic polymer coating, ligand exchange with thiolate molecule/polymer, polyhistidine coating, polydopamine coating and hyperbranched polyglycerol grafting. It is shown that these coating methods produce a variety of primary amine-terminated nanoparticles and nanoparticles with controlled charge/functional groups. The described coating approaches offer a general guideline to prepare various coated nanoparticles and can be adapted to new nanoparticles of interest.