ABSTRACT
No apparent skin injury or scar was documented in any of the test areas. ere was a slight increase in pigmentation at the one week follow-up for some of the test sites but there was no hypopigmentation or textural changes. Selective fat loss was evident on gross specimens by a smooth indentation along the surface of the animal of a size and shape similar to that of the cooling device. A reduction of fat in the super cial fat layer was documented at 3.5 months with 80% of the super cial fat layer removed for a total fat loss of 40% from the procedure. Histology demonstrated a marked reduction of fat with a reduced distance between fat septae.
