ABSTRACT

Angiogenesis can be defined as structural expansion of a microvascular bed

occurring as outgrowth from the existing vasculature. This is distinct from

vasculogenesis, which refers to the development of new vasculature, as most

obviously occurs in development. Angiogenesis is a widely studied and very

complex process. Almost daily, new twists are discovered as additional factors

that initiate or regulate the process are discovered.