ABSTRACT

The ability of the human body to control the ow of blood following vascular injury is paramount to continued survival. The process of blood clotting and then the subsequent dissolution of the clot, following repair of the injured tissue, is termed hemostasis. To stop bleeding, the injured vessel wall is processed by primary platelet-mediated aggregation (Figure 19.1a), a secondary blood coagulation pathway (Figure 19.1b), retraction of brin clot (Figure 19.1a), and brinolysis after vascular constriction, as described in the following.