ABSTRACT

Introduction According to the World Health Organization (WHO), from a total of 58 million deaths worldwide in 2005, cancer accounted for 7.6 million (13%). Deaths from cancer are projected to continue rising, with an estimated 9 million people dying from cancer in 2015 and 11.4 million dying in 2030, by which time it will be the leading cause of death. The high mortality is also accompanied by significant morbidity and cancer has a huge economic burden. It is estimated that 40% of cancers can be prevented by modifying several risk factors. This chapter deals with methodological aspects of assessing risk factors for cancer, cancer prevention strategies, and endpoints in cancer prevention studies.