ABSTRACT
During the last several decades, basic scientists and clinical investigators have rapidly advanced our understanding of perioperative fluid management. The results of those investigations, which are the substance of this book, have helped make great progress in quantifying the physiological effects of fluid replacement and demonstrating the adverse effects of insufficient or excessive fluid administration. However, existing data are insufficient to facilitate development of evidence-based standards that apply to individual patients undergoing diverse surgical procedures. To reach those evidence-based standards requires that investigators overcome many challenges.
