ABSTRACT
Ketamine:
Has a pKa of 7.5
Has two geometric stereoisomers
Is more lipid soluble than thiopentone
Has local anaesthetic properties
Effects are mediated by central agonism at the N-methyl-D-aspartate (NMDA) receptor
Ketamine:
Has a pKa of 7.5
Has two geometric stereoisomers
Is more lipid soluble than thiopentone
Has local anaesthetic properties
Effects are mediated by central agonism at the N-methyl-D-aspartate (NMDA) receptor