ABSTRACT
Malaria is the world’s most important tropical parasitic disease that kills more people than any other communicable disease with the exception of tuberculosis. The causative agents in humans are four species of Plasmodium protozoa: P. falciparum, P. vivax, P. ovale, and P. malariae. Of these, P. falciparum accounts for the majority of infections and is the most lethal. Malaria is a public health problem today in more than 106 countries, inhabited by a total of 3.4 billion people-50% of the world’s population. Worldwide prevalence of the disease is estimated to be on the order of 135287 million clinical cases each year. Mortality due to malaria is estimated to be in the range of 473,000-789,000 each year.
