ABSTRACT
This chapter focuses on pulmonary complications that can be viewed as iatrogenic – that is, resulting in some way from the surgical and pharmacological manipulation of the recipient of a solid-organ transplant. The spectrum of microorganisms responsible for post-transplantation pulmonary infections is similar among the various solid-organ transplantation populations and is discussed in detail in the sections that follow. Treatment of active tuberculosis in organ transplant recipients involves the use of combination therapy as per standard guidelines for the general population. Among lung transplant recipients, the non-tuberculous myco-bacteria may be more common than Mycobacterium tuberculosis as a cause of pulmonary infections. Cytomegalovirus is the most common viral pathogen encountered in all solid-organ recipient populations. Risk factors for development of primary graft dysfunction include donor female gender, donor African American race, donor age and a recipient diagnosis of primary pulmonary hypertension.
