ABSTRACT
This chapter focuses on selected highlights and findings in treatment-associated lung tumours, concentrating on survivors of adult cancer. Given the high baseline incidence rates of lung cancer in the general population, even a small increase in the relative risk can translate into large absolute risk, which is considered the optimal measure of disease burden in a population. Cigarette smoking is thought to have a multiplicative effect on the risk of lung cancer following breast cancer radiotherapy. Breast cancer survivors may also be at increased risk of death from second cancers, especially when treated with radiotherapy at a young age. The importance of tobacco use in the subsequent risk of lung cancer among Hodgkin’s lymphoma patients has been established through analytical studies. The number of survivors with multiple primary malignancies is rising, with independent cancers representing about one in six incident cancers.
