ABSTRACT
Historical review 894 Principles of radiation therapy 895 Methods of radiation treatment delivery 895 Types of ionizing irradiation 895 Radiation fields 896 Radiation dose 897 Radiation treatment planning 898 Hodgkin disease 898 Favorable presentations of stage I-II 898 Unfavorable presentations of stage I-II 899 Stage III-IV 900 Relapsed disease 901 Follicular lymphoma 901 Stage I-II 901 Stage III-IV 902 Palliation 902 Marginal zone, including MALT lymphomas 902 Large B cell lymphoma 902 Stage I-II 902
Stage III-IV 903 Salvage therapy 904 Primary mediastinal large B cell lymphoma 904 Mantle cell lymphoma 904 Plasma cell neoplasms 904 Burkitt lymphoma 905 Lymphoblastic lymphoma/leukemia 905 Natural killer/T cell lymphoma, nasal type 905 Anaplastic large cell lymphoma 905 Peripheral T cell lymphoma 905 The primary cutaneous lymphomas 906 Mycosis fungoides 906 Follicle center cell lymphoma 906 Marginal zone lymphoma 906 Anaplastic large cell lymphoma 906 Other primary cutaneous lymphomas 907 Key points 907 References 907
Radiation therapy was first used for the treatment of lymphoma more than a century ago, within just a few years of the discovery of x-rays by Roentgen. The first reports included patients with Hodgkin disease and the non-Hodgkin lymphomas.1,2 The responses to x-ray exposure at times were described as ‘almost magical’ and early radiologists recognized that curative treatment programs for these diseases might be developed. However, they also appreciated a need for a better understanding of the disease entities and better radiation therapy technology to achieve these goals.
