ABSTRACT
Nanotechnology is an emerging interdisciplinary area, which has many applications including drug delivery. Nanocarrier drug delivery involves target drugs enclosed in a particular ceramic, polymer, and/or amphiphilic matrix. Controlled-release, nano-platform availability for combinatorial therapy and specic targeting are the promises of nanotechnology. Many bio-inspired ceramics, capable of bioactive responses and biodegradation, have been innovated in past three to four decades. Ceramic nanomaterials with mesoporous and microporous surface morphology have proved to possess desired characteristics that are used in nanomedicine for targeted delivery of bio-macromolecules. Biomaterial is a substance that has been engineered to take a form that, alone or as part of a complex system, is used to direct, by control of interactions with components of living systems, the course of any therapeutic or diagnostic procedure, in human or veterinary medicine [1]. In broad sense, biomaterials are designed to treat disorders of a biological system, which perform their function by interfering with the system without disturbing its anatomical and/or physiological integrity. The major difference of biomaterials from other classes of materials is their ability to remain in a biological environment without damaging the surroundings and without being damaged in that process. Thus, biomaterials are solely associated with the health-care domain and must have an interface with tissues or tissue components [2,3]. The last three to four decades represent the scientic advancement in innovative use of ceramics in biomedical applications such as skeletal repair and construction. Ceramics can be dened as solid compounds that are formed by chemical reaction between a metal and a nonmetallic elemental solid or between a nonmetal and nonmetallic elemental solids [4-11].
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