ABSTRACT

The leading drug tester, Don Catlin, is reported to have examined some 20 urine samples that tested positive for tetrahydrogestrinone (THG). Marion Jones, who won three gold medals and two bronze medals at the Sydney Olympics in 2000, admitted THG use in 2007 and was stripped of these medals by the International Olympic Committee and the International Association of Athletics Federations. Detailed analysis led them to deduce the structure of THG, which they then synthesized to check its ID, so to speak. One look at some of the athletes found to have taken it makes we think that that THG has very strong anabolic effects. More scientifically, a comparison has been made of the binding of four potent androgens, the natural testosterone, together with synthetic dihydrotestosterone, methyltrienolone and THG, showed that THG had the highest affinity for the human androgen receptor.